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課程名稱 |
基因體學
GENOMICS |
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開課學期 |
98-1 |
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授課對象 |
生物資源暨農學院 農業化學研究所 |
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授課教師 |
洪傳揚 |
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課號 |
AC5077 |
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課程識別碼 |
623EU4450 |
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班次 |
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學分 |
1 |
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全/半年 |
半年 |
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必/選修 |
選修 |
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上課時間 |
星期一9,A,B(16:30~20:10) |
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上課地點 |
農化二B10 |
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備註 |
本課程以英語授課。與Shen副教授合授。12月21-25，28日晚上6-9時上課，不可缺席
總人數上限：80人 |
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Ceiba 課程網頁 |
http://ceiba.ntu.edu.tw/981genomicsAC |
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課程簡介影片 |
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核心能力關聯 |
核心能力與課程規劃關聯圖 |
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課程大綱
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為確保您我的權利,請尊重智慧財產權及不得非法影印
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課程概述 |
This course will (1) provide an overview of these new approaches; (2) develop your problem solving skills to address specific aspects of gene expression regulation and strategies for defining gene functions; and (3) inform you of the applications of these new technologies in life science and medical researches. |
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課程目標 |
The recent accomplishment in sequencing the genomes of human, Arabidopsis, rice, Drosophila, yeast and many other microorganisms has provided an unprecedented opportunity to study the molecular mechanisms of cell differentiation and organism development. The overall aim of the course is to equip students with a solid foundation in new approaches that integrate genetics, molecular biology, physics, mathematics and computer science to answer biological questions in novel ways. |
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課程要求 |
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預期每週課後學習時數 |
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Office Hours |
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指定閱讀 |
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參考書目 |
1. ”Genomes 3 ”, Ed. by Brown, 2006, published by Wiley-Liss.
2. “Bioinformatics: Sequence and Genome Analysis”, Ed. by Mount, 2004, published by Cold Spring Harbor Laboratory Press.
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評量方式
(僅供參考) |
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週次 |
日期 |
單元主題 |
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第1週 |
9/14 |
Overview of the course
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第2週 |
9/21 |
Review of genomes and transcription-Transcription in prokaryotic and eukaryotic cells
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第3週 |
9/28 |
Genome sequencing
Genomics: Tools needed to map a genome
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第4週 |
10/05 |
Genome mapping – genetic maps vs physical maps
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第5週 |
10/12 |
DNA-marker-based genetic linkage mapping
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第6週 |
10/19 |
Linking of genetic maps and physical maps
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第7週 |
10/26 |
Genome cloning
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第8週 |
11/02 |
Midterm exam
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第9週 |
11/09 |
Two approaches taken in sequencing the human genome
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第10週 |
11/16 |
Bioinformatics: gene identification and annotation
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第11週 |
11/23 |
NCBI, theory and application
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第12週 |
11/30 |
Supports of computation predictions- EST (expressed sequence tags), cDNA library construction and sequencing, |
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第13週 |
12/07 |
UniGene Collection
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第14週 |
12/14 |
Genome expression -basic research with microarrays
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第15週 |
12/21 |
Alternative uses of DNA microarrays
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第16週 |
12/28 |
Applied research with DNA microarrays
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第17週 |
1/04 |
Final exam |
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